Genome Research Biorxiv. Watermelon is one of the most important fruit … Background

Watermelon is one of the most important fruit … Background Current microbial sequencing relies on short-read platforms like Illumina and DNBSEQ, favored for their low cost and high accuracy. But most of them are difficult to be genetically transformed. Here, we present a chromosome-level assembly of … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Gene prediction has remained an active area of bioinformatics research for a long time. Resolving genome-epigenome coevolution requires accurate multi-omic … While protein-coding genes are characterized increasingly well, 99% of the human genome is non-coding and poorly understood. The use of this approach has … We present a method for detecting evidence of natural selection in ancient DNA time-series data that leverages an opportunity not utilized in previous scans: testing for a … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution The crab-eating macaques ( Macaca fascicularis ) and rhesus macaques ( M. It is considered the longest-lived vertebrate on Earth, with an estimated lifespan of 392±120 years. Here, we newly developed a genome-free … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Début 2020, bioRxiv a joué un rôle important dans la diffusion rapide de la connaissance concernant la pandémie de COVID-19 causée par le coronavirus SARS-CoV-2, en … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Début 2020, bioRxiv a joué un rôle important dans la diffusion rapide de la connaissance concernant la pandémie de COVID-19 causée par le coronavirus SARS-CoV-2, en … Abstract The Greenland shark (Somniosus microcephalus) is the longest-lived vertebrate known, with an estimated lifespan of ~ 400 years. A high-quality reference genome of Meleagris gallopavo is essential for turkey … The remarkable pace of genomic data generation is rapidly transforming our understanding of life at the micron scale. An overview diagram for seed plants … Escherichia coli strain C is the last of five E. … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Skeletal muscle, the largest human organ by weight, is relevant in several polygenic metabolic traits and diseases including type 2 diabetes (T2D). In a landscape analysis of 1024 lung adenocarcinomas (LUAD) with deep whole-genome … The Cucurbitaceae contains multiple species of important food plants. The … Understanding lung cancer evolution can identify tools for intercepting its growth. Omics-based tomato research has … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Chickens are a crucial source of protein for humans and a popular model animal for bird research. Still, gene prediction in large eukaryotic genomes presents a challenge that must be addressed by new algorithms. mulatta ) are widely studied nonhuman primates in biomedical and evolutionary research. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution The previous genome is of draft quality and partly based on the chicken (Gallus gallus) genome. bioRxiv is operated by openRxiv, a non-profit … Dire wolves ( Aenocyon dirus ) are extinct predators of Pleistocene North America. The OzWheat genome … Auxenochlorella are diploid oleaginous green algae that are highly amenable to genetic transformation by homologous recombination, providing great potential for discovery … Heritability, the proportion of phenotypic variance explained by genetic factors, can be estimated from pedigree data [1][1], but such estimates are uninformative with respect to … Understanding the taxonomic and functional diversity of the human oral microbiome requirescomprehensive genomic catalogs. coli strains (C, K12, B, W, Crooks) designated as safe for laboratory purposes whose genome has not been sequenced. One of the most significant achievements has been the sequencing of the first human genomes, which … Recent advances in long-read sequencing (LRS) and assembly algorithms have made it possible to create highly complete genome assemblies for humans, animals, plants … The UK Biobank project is a large prospective cohort study of ~500,000 individuals from across the United Kingdom, aged between 40-69 at recruitment. This gap is due to a lack of tools for engineering … Our analysis provides evidence of conserved genome synteny despite the long divergence times of this group, but we also highlight inconsistencies in chromosome naming … India has been underrepresented in whole genome sequencing studies. Identifying genetic … There is increasing recognition that a single, monoploid reference genome is a poor universal reference structure for human genetics, because it represents only a tiny … Defining the minimal genetic requirements for cellular life remains a fundamental question in biology. Sequence polymorphisms in outcrossing tree species pose … Pigs are crucial sources of meat and protein, valuable animal models, and potential donors for xenotransplantation. Despite progress, the genomic aberrations underpinning … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Gene prediction has remained an active area of bioinformatics research for a long time. Despite the emergence of imputation as a reliable genotyping strategy for … Epigenetic alterations co-evolve with genetic mutations to drive carcinogenesis and treatment response. Together … Arabidopsis thaliana was the first plant for which a high-quality genome sequence became available. The publication of the first reference genome sequence almost 25 years … As genomic research continues to advance, sharing of genomic data and research outcomes has become increasingly important for fostering collaboration and accelerating … About bioRxiv bioRxiv (pronounced "bio-archive") is a free online archive and distribution service for unpublished preprints in the life sciences. A key indicator of this regulation is replication … Background The agamid dragon lizard Pogona vitticeps is one of the most popular domesticated reptiles to be kept as pets worldwide. … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution. While it is broadly accepted that this also applies to measles, the exact … The Greenland shark ( Somniosus microcephalus ) is known for its slow metabolism and deep-sea habitat. We generated 2,762 high coverage genomes from India––including individuals from most geographic regions, speakers of all … Here, we describe expansion in situ genome sequencing (ExIGS), a technology that enables sequencing of genomic DNA and superresolution localization of nuclear proteins in single cells. We present the human reference oral … Many infectious diseases are thought to have emerged in humans after the Neolithic revolution. Watermelon is one of the most important fruit … Gene prediction has remained an active area of bioinformatics research for a long time. In the … It includes a chronology of genome publications, and cladograms to display the phylogenetic relationships among the sequenced plants. However, the existing reference genome for pigs is incomplete, with thousands of segments and … For over a century, Australian wheat breeders have successfully adapted wheat to a broad range of climatic conditions and crop management practices. We … Tomato is a globally vital crop and model system for fleshy fruit development, with profound agricultural and economic significance. The publication of the first reference genome sequence almost 25 years … All of life encodes information with DNA. polymorpha have an unusual 67 kb mitochondrial genome containing numerous tandem repeats, making it the largest observed in Eumetazoa. However, these methods … This bias is particularly problematic when the reference genome is evolutionarily distant from the paleogenome 28,29, as is the case for the dire wolf. Advances in machine learning combined … The Human Pangenome Reference Consortium (HPRC) presents a first draft human pangenome reference. It’s now considered one of the leading platforms for … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution bioRxiv accepts preprints of articles covering all aspects of research in the life sciences. While tools for sequencing, synthesis, and editing of genomic code have transformed biological research, intelligently composing new biological systems would … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution Most research journals allow posting on preprint servers such as bioRxiv prior to publication. Still, gene prediction in large eukaryotic genomes presents a challenge that must be … Modern agriculture demands precise genomic prediction to accelerate elite crop breeding, yet traditional genomic prediction approaches, such as genomic best linear unbiased … The last 20 years have been a remarkable era for biology and medicine. Despite progress, the genomic aberrations underpinning … We report a genome-wide association meta-analysis of 20,183 ADHD cases and 35,191 controls that identifies variants surpassing genome-wide significance in 12 independent … Osteosarcoma is the most common primary cancer of bone with a peak incidence in children and young adults. Yet this data stream also creates challenges for team … Arabidopsis thaliana , a model plant, is intensively researched because of the intrinsic advantages associated with its life cycle, genetics, and other characteristics. A rich variety of phenotypic and health-related information … bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution It is a long-term challenge to undertake reliable transcriptomic research under different circumstances of genome availability. Although phenotypically similar to living wolves ( Canis lupus ), dire wolves have yet to be placed confidently in the canid … Here we investigated the possibility that SARS-CoV-2 RNAs can be reverse-transcribed and integrated into the human genome and that transcription of the integrated … To extend the frontier of genome editing and enable the radical redesign of mammalian genomes, we developed a set of dead-Cas9 base editor (dBEs) variants that allow … Arabidopsis thaliana was the first plant for which a high-quality genome sequence became available. Bioinformatics Biophysics Cancer Biology Cell Biology Clinical Trials Developmental Biology Ecology Epidemiology Evolutionary Biology Genetics Genomics Immunology Microbiology … Genome Research is an international, continuously published, peer-reviewed journal that features outstanding original research providing novel insights into the genome biology of all organisms, including … Today, bioRxiv is widely used for various fields, including genomics, neuroscience, evolutionary biology, bioinformatics, and cell biology. Several factors … The genome is a sequence that completely encodes the DNA, RNA, and proteins that orchestrate the function of a whole organism. The integration of genome data with electronic health records, driven by large biobank studies, has advanced human genetics by allowing systematic exploration of … The Indian Cancer Genome Atlas (ICGA) has launched a multi-omics data portal and released the first clinically correlated molecular dataset of Indian breast cancer patients, … The success of CRISPR genome editing studies depends critically on the precision of guide RNA (gRNA) design. When posting an article, the author assigns it to one of the following categories: We also found that D. The capacity of breeding in captivity also … To exploit allelic variation in Hordeum vulgare subsp. DNA replication in humans requires precise regulation to ensure accurate genome duplication and maintain genome integrity. Genomic exploration continually reveals novel microbial lineages, often exhibiting extreme genome … We report a genome-wide association meta-analysis of 20,183 ADHD cases and 35,191 controls that identifies variants surpassing genome-wide significance in 12 independent … Osteosarcoma is the most common primary cancer of bone with a peak incidence in children and young adults. spontaneum , the Wild Barley Diversity Collection was evaluated for several agronomic traits and subjected to paired-end … CRISPR-Cas9 genome editing is a promising technique for clinical applications, such as the correction of disease-associated alleles in somatic cells. A list of journal policies can be found on Wikipedia and SHERPA/RoMEO. psekvu2ov
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